QuickView for dihydrofolate reductase;jsessionid=751D0F22D93BA9CC162C1512FB2A95B1;jsessionid=A10841CB22D44A8A8DE1B4D3A6FD7073 (gene)
- Gene Symbol:
- DHFR
Bos taurus - Full name:
- dihydrofolate reductase
- Synonyms:
- N/A
- Genomic Location:
- Chr 7: 81622761-81638585
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
oxidoreductase activity, acting on the CH-NH group of donors | nucleic acid binding | mRNA binding | catalytic activity | organic cyclic compound binding | dihydrofolate reductase activity | drug binding | heterocyclic compound binding | oxidoreductase activity | RNA binding
GO Biological Process
regulation of cellular response to oxidative stress | regulation of response to oxidative stress | pteridine-containing compound biosynthetic process | response to drug | polyol metabolic process | tetrahydrofolate metabolic process | cellular process | oxidoreductase activity, acting on the CH-NH group of donors | regulation of removal of superoxide radicals | positive regulation of nitric-oxide synthase activity | positive regulation of oxidoreductase activity | positive regulation of catalytic activity | folic acid-containing compound biosynthetic process | regulation of cellular process | regulation of metabolic process | one-carbon metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | folic acid-containing compound metabolic process | tetrahydrobiopterin biosynthetic process | tetrahydrofolate biosynthetic process | response to stimulus | cellular nitrogen compound biosynthetic process | alcohol metabolic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular biosynthetic process | pteridine-containing compound metabolic process | regulation of cellular response to stress | positive regulation of monooxygenase activity | organic hydroxy compound metabolic process | response to nitrogen compound | regulation of superoxide metabolic process | nitrogen compound metabolic process | coenzyme biosynthetic process | regulation of catalytic activity | regulation of nitric-oxide synthase activity | cofactor biosynthetic process | small molecule metabolic process | response to methotrexate | cellular amide metabolic process | tetrahydrobiopterin metabolic process | biosynthetic process | diol biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | drug metabolic process | carboxylic acid metabolic process | positive regulation of molecular function | response to organic substance | response to antineoplastic agent | dihydrofolate reductase activity | regulation of response to reactive oxygen species | metabolic process | oxidation-reduction process | organic substance metabolic process | amide biosynthetic process | regulation of oxidoreductase activity | response to organic cyclic compound | organic acid metabolic process | regulation of reactive oxygen species metabolic process | response to organonitrogen compound | cellular modified amino acid metabolic process | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | oxidoreductase activity
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular
